Torque Teno Virus as a Novel Biomarker Targeting the Efficacy of Immunosuppression After Lung Transplantation
نویسندگان
چکیده
منابع مشابه
Pre-Transplant Plasma Torque Teno Virus Load and Increase Dynamics after Lung Transplantation
BACKGROUND The human Torque Teno virus (TTV) causes persistent viremia in most immunocompetent individuals. Elevated TTV levels are observed after solid organ transplantation and are related to the extent of immunosuppression especially during the phase of maintenance immunosuppression. However, the extent to which the TTV increase in the early phase post-transplantation is associated with the ...
متن کاملTorque teno virus: a ubiquitous virus
Torque teno virus (TTV) is a non-enveloped human DNA virus isolated by Nishizawa et al. in 1997.1 TTV, recently classified as the Alphatorquevirus genus within the Anelloviridae family by the International Committee on Taxonomy of Viruses (ICTV), was the first human virus with a single-stranded circular DNA genome to be identified.2 Thus far, five main genetic groups (Groups 1–5) involving at l...
متن کاملTorque teno virus: a ubiquitous virus☆
caid et al. showed that the TTV encodes a miRNA in vivo that orque teno virus (TTV) is a non-enveloped human DNA virus solated by Nishizawa et al. in 1997.1 TTV, recently classified s the Alphatorquevirus genus within the Anelloviridae family by he International Committee on Taxonomy of Viruses (ICTV), as the first human virus with a single-stranded circular DNA enome to be identified.2 Thus fa...
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TTV has been recently identified as a causative agent of non-A to non-G hepatitis. However, the exact role of this virus in the pathogenesis of chronic liver disease (CLD) and the development of hepatocellular carcinoma (HCC) remain controversial. To clarify these issues, the prevalence of this virus and its impact on the severity of liver disease and development of HCC among Egyptian patients ...
متن کاملTorque Teno virus viremia correlates with intensity of maintenance immunosuppression in adult orthotopic liver transplant.
TO THE EDITOR—We read with interest the recent article by Béland et al, detailing torque teno virus (TTV) kinetics in pediatric orthotopic liver transplant (OLT) recipients [1]. Interestingly, the authors show that TTV load increased with the number of immunosuppressive agents received. TTV viremia, which is normally at about 2 log10 in healthy subjects, has been shown to increase (up to 4 log1...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2018
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jiy452